The Absorption of Fat in Partially, and in Completely Depancreatized Dogs

It was found that dogs with a subcutaneous transplant secreting and discharging pancreatic juice externally absorbed no more fat than dogs in which the pancreatic remnant was undergoing rapid atrophy and sclerosis. Hence, the condition of the pancreatic tissue remaining in the body does not influence the amount of fat absorbed by the intestine. The absorption of fat by the intestinal mucous membrane is always markedly disturbed when the pancreatic secretion is excluded from the intestine. After the complete removal of all pancreatic tissue from an animal, the absorption of considerable amounts of fat can still take place.